AI for Science

What happens when you stop thinking of AI as a tool and start thinking of it as an operator? Not a copilot that helps you write emails faster, but an autonomous system that builds products, acquires customers, writes code, sends outreach emails, generates traffic reports, and makes strategic decisions — while you sleep. That’s the […]

The Best Longevity Supplement Stack in 2026: What I Actually Take and Why Most longevity stacks are marketing. Someone finds a study suggesting compound X extends lifespan in worms, another study showing compound Y improves mitochondrial function in mice, and suddenly they’re selling you a 15-ingredient blend that costs $300/month. None of them have actually

Epigenetic Age Tests Compared: TruMe, Elysium Index, Tally Health, and What They Actually Measure (2026) You probably know your chronological age—the number of years you’ve existed. But what you really care about is your biological age: how fast your body is aging at a cellular level. Epigenetic clock tests promise to measure exactly that. It

NAD+ Precursors Compared: NMN vs NR vs Niacin vs NAM — The Complete 2026 Guide If you’ve spent any time in the longevity world, you’ve heard that NAD+ is critical for aging. Older organisms have lower NAD+. NAD+-restoring interventions extend lifespan in animals. Therefore, you should take NAD+ precursors to stay young. The logic feels

Semaglutide vs Tirzepatide for Longevity: Beyond Weight Loss, What Does the Data Show? (2026) GLP-1 agonists have taken over the health conversation, but most people are asking the wrong question. They’re obsessing over weight loss when the real story is what these drugs do to your metabolism, inflammation, and cardiovascular risk. I’ve reviewed every major

Senolytics Compared: Fisetin, Dasatinib + Quercetin, and Navitoclax — What the Evidence Shows (2026) Most longevity interventions feel like shots in the dark: hope the mechanism holds up, hope it translates to humans, hope you survive the side effects. Senolytics are different. They target something real—senescent cells—and we’ve known what they do to aging for

Urolithin A vs CoQ10: Which Mitochondrial Supplement Is Worth Taking? (2026) Mitochondria are the aging cell’s achilles heel. As you age, your mitochondria become dysfunctional—slower at producing ATP, generating more oxidative stress, and failing to trigger the quality control mechanisms that normally clear damaged mitochondria. Both urolithin A and CoQ10 claim to fix this, but

Fisetin vs Quercetin: Which Senolytic Flavonoid Is More Effective? (2026) Senolytics—drugs or compounds that selectively kill senescent cells—have become the hottest thing in longevity science since NAD+ precursors. And the two compounds most people ask me about are fisetin and quercetin. Both are natural flavonoids. Both kill senescent cells in lab conditions. Both are cheap.

Rapamycin vs Metformin for Longevity: What the Evidence Actually Shows (2026) If you’ve read anything about longevity science in the past five years, you’ve seen rapamycin and metformin compared endlessly. I’ve literally made investments in companies developing both compounds for aging. But here’s what bothers me: most comparisons are oversimplified. People say “rapamycin is stronger”

BPC-157 vs TB-500: Which Peptide Is Better for Recovery and Healing? (2026) I’ve been tracking peptide research since 2015, when these compounds were barely on the radar outside of elite sports science circles. Today, BPC-157 and TB-500 are two of the most sought-after compounds in the longevity and recovery space, with thousands of people ordering