Author name: Ryan Bethencourt

Biotech investor, founder, and writer. Co-founded IndieBio, the world's largest seed biotech accelerator. CEO of Wild Earth. 180+ early-stage biotech investments. Writing about longevity science, AI, and what comes next at Grey Area Labs and in the Accelerated newsletter.

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AI for Science

How AI and DeSci Will Transform the S&P 500 Landscape

Disclaimer: Never financial or medical advice and written in collaboration with ChatGPT and Grok In the fast-evolving world of technology, the S&P 500 faces an unprecedented wave of AI disruption over the next decade. With artificial intelligence and other exponential technologies converging, traditional sectors are set for a massive overhaul. In fact, Morgan Stanley analysts […]

Peptides & Advanced Therapeutics, Longevity Molecules

The Ultimate Guide to Peptides for Longevity: Benefits, Risks, and Latest Research

Introduction: Why Peptides Are the New Frontier in Longevity Science For decades, researchers have searched for the key to extending human lifespan — from calorie restriction to supplements like resveratrol, NAD+ boosters, and rapamycin. But a new category of therapies is now emerging as one of the most promising tools in the fight against aging: peptides.

AI for Science

AI and CRISPR: Optimizing Gene Editing Efficiency and Safety

Artificial intelligence is changing the way scientists design CRISPR experiments. CRISPR-Cas9 has revolutionized gene editing, but picking the right guide RNA (gRNA) to direct the Cas9 enzyme remains difficult because mismatched sequences can lead to off-target cuts and inconsistent efficiency. Traditional design tools rely on alignment rules or empirical scoring, which struggle to balance on-target

AI for Science

Revolutionizing Protein Engineering with Generative Models

Introduction AlphaFold and its successor ESMFold have transformed structural biology by predicting protein structures from amino acid sequences with high accuracy. While these predictors have revolutionized our ability to understand existing proteins, a new frontier is emerging: generative models that design entirely new proteins with desired functions. These models move beyond structure prediction to actively

Longevity Molecules

Top Longevity Supplements: What Works and Why

Important Notice: This article is provided for informational and educational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. In the ever-evolving world of health and wellness, longevity supplements have captured widespread attention, promising to extend not just lifespan but healthspan—the years we live vibrantly and free from

AI for Science

AI-Driven ADMET Predictions in Drug Discovery

Artificial intelligence is reshaping how pharmaceutical scientists evaluate absorption, distribution, metabolism, excretion and toxicity – collectively called ADMET. Poor ADMET properties cause a large portion of late-stage drug failures, and traditional assays are costly and slow. Machine‑learning (ML) models now offer rapid, cost‑effective alternatives. A 2025 review of ML applications in ADMET prediction found that

Peptides & Advanced Therapeutics

Complete Guide to Weight Loss Peptides: What You Need to Know

Peptides for Weight Loss: Do They Work? (Complete Science-Backed Guide) Updated: August 18, 2025 • Reading time: ~20 minutesMedical disclaimer: This article is for educational purposes only and is not medical advice. Talk to a qualified clinician before using any supplement or medicine. Hook: Can a simple peptide injection really melt away pounds? It’s a question fueling tens

AI for Science

Future of Research: Robotics, AI, and Digital Twins Integrated

Modern biomedical and materials research generates more data and experimental possibilities than any human lab team can handle. Researchers find themselves spending countless hours on repetitive tasks like weighing reagents, mixing solutions, and logging sample data. In an age where artificial intelligence can drive cars and draft literature reviews, it makes sense that the wet

Longevity Molecules

Understanding Zombie Cells and Their Impact on Aging

🧟 Zombie Cells: The Hidden Cause of Aging Aging is one of life’s greatest mysteries. Why do some people remain active and vibrant into their 90s while others struggle with chronic disease by their 50s? Scientists have uncovered many drivers of aging, but one discovery stands out as especially promising: senescent cells, also called zombie

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